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Genetic testing for targeted cancer treatment

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Created: 14/02/2024
Edited: 14/02/2024
Written by: Kate Forristal

Is it possible not to benefit from one of these types of targeted treatments despite receiving them?

While targeted treatments aim to address specific genetic alterations in cancer cells, individual responses can vary. Factors such as the tumour's unique characteristics and overall health play a role in treatment outcomes.

Why undergo the analysis?

Genetic analysis provides valuable insights into the genetic makeup of the cancer, enabling healthcare professionals to tailor treatments for maximum efficacy. This personalised approach enhances the chances of successful outcomes.

 

When should the analysis be done?

The timing of genetic analysis is crucial. It is typically recommended at the time of cancer diagnosis to guide treatment decisions promptly. However, in some cases, re-analysis may be beneficial during the course of treatment.

 

What sample is required?

To conduct genetic testing, a sample of the tumour tissue is often required. This can be obtained through procedures such as biopsies or surgical resections.

 

Is any type of prior preparation necessary?

In most cases, no specific preparation is needed for genetic testing. However, your healthcare team will provide guidance based on your individual case.

 

How is it utilised?

The genetic information obtained from testing helps identify specific mutations or alterations in the cancer cells. This information guides the selection of targeted therapies that are most likely to be effective against those particular genetic changes.

 

What are the normal values?

Genetic testing does not have "normal" or "abnormal" values in the traditional sense. Instead, the results indicate the presence or absence of specific genetic mutations that can inform treatment decisions.

Genetic Marker

Normal Range

Significance

Gene A

Present

Linked to 25% of cases

Gene B

Altered

Predicts positive response to Drug Z

Gene C

Absent

Associated with favourable prognosis

 

What does it mean to have altered values?

Altered values signify the presence of specific genetic mutations or alterations. This information is crucial for selecting targeted therapies designed to address the identified genetic abnormalities.

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